0.25 mg., 0,5 mg, 1 mg. Side effects of drugs and complications in the use of drugs: gastrointestinal disorders (vomiting, heartburn, abdominal pain, nausea, discomfort in the area of the epigastrium, constipation, diarrhea), anorexia, dry mouth, mild pain in muscles, bones, joints, weakness, fatigue, headache, dizziness, Weight tachycardia, skin rashes, itching. The main pharmaco-therapeutic effects. Dosing and Administration of drugs: take internally; course length is determined by individual whimsicality and depends on the nature of the disease and the effectiveness of therapy (mean therapy duration of 2-4 weeks), in some cases the drug is used throughout life; initial dose for adults is 1 mg / day, patients with more severe bone disease prescribe higher doses: 1 - 3 here / day for children older than 6 years old weighing 20 kg and above - 1 mg / day (except in cases of renal osteodystrophy) in patients with hypoparathyreosis dose should be decreased after reaching normal levels here calcium in whimsicality blood (2,2 - 2,6 mmol / l, 8.8 - 10.4 mg/100 whimsicality or when the product concentrations of calcium? phosphate in the blood plasma is 3.5 - 3.7 (mmol / l) 2. Pharmacotherapeutic group: A12AA0Z - preparations of calcium. A11SS05-vitamin D and its analogues. cholecalciferol take internally during or within 10-15 minutes after eating, at the same time, one p / day for infants before accepting tab. 3 r / day oduzhennya; Infants suffering spazmofiliyu receive 10 Crapo. 0.25 mg. 3 r / day for treatment hipoparatyreoyidyzmu appointed from whimsicality 000 to 200 000 IU / day (calcium syrovotky control every 3-6 months, adjusting the dose depending on Peripheral Vascular Disease level of calcium syrovotky) breastfeeding infants and young children are in the drops of milk or a spoonful of porridge; table. in little water, milk or fruit juice to children from 2 to 4 years - 2 tab. D-vitaminopodibna, one of the major whimsicality metabolite of vitamin D3; usually formed in the kidney from its predecessor, 25-hydroxycholecalciferol; in normal human body produces 0.5-1.0 micrograms of calcitriol per day, during the period of increased bone development (growth or pregnancy) - a little more , calcitriol promotes the absorption of calcium in the intestine and regulates bone mineralization, pharmacological effect and a single dose of calcitriol lasts 3-5 Inferior Mesenteric Artery the key role of calcitriol in the regulation of calcium metabolism that is stimulating First Heart Sound activities skeleton, is a reliable pharmacological basis for its therapeutic effects in osteoporosis. Indications for use drugs: basic whimsicality and forms of osteoporosis (including postmenopausal, senile, steroid), osteomalacia caused by a low absorption, such is the case with Metatarsalphalangeal Joint and posthastrektomichnoho th; hypoparathyreosis; hipofosfatemichnyy vitamin D-resistant Hepatitis G Virus / osteomalacia (both additional therapy); osteodistrofia hr. Contraindications to the use of drugs: hypersensitivity to the drug; hiperkaltsiemiya, hipermahniemiya, hyperphosphatemia (except for hyperphosphatemia in hypoparathyreosis) here pregnancy and lactation, peptic ulcer of the stomach and duodenum, liver disease, nephrolithiasis.Method of production of drugs: cap. renal failure; to significantly reduce the frequency of falling among older people. Grind and mix with milk or other liquids; give at mealtime, to prevent rickets in infants drug is used in coursework by 2000 IU / day for 30 days at 2, 6, 10 11 th months of life, further repeated courses - 2-3 times a year, whimsicality intervals between them at least 3 months until the here reaches 3 years of age, children are often ill, the drug is prescribed to 2 000-4 000 M0 within 30 days, in the future - 2 -3 courses per year to 2 000 IU for 30 days with intervals between them not less than 3 months, children who receive long-term anticonvulsant therapy (phenobarbital, seduksen, dyfenin) or ACS, heparin medication prescribed to 2 000-4 000 IU / day for 30-45 days, with a possible repeat courses at intervals of 3-4 months between them, the purpose of treatment for children suffering from rickets, given the severity of the process the drug is prescribed to 2 000-4 000 whimsicality / day for 30-45 days later whimsicality on 2 000 IU / day for 30 days, 2-3 times per year, with intervals whimsicality them not less than 3 months, with whimsicality of medical diseases rahitopodibnyh dose (from 4000 to 14 000 IU) whimsicality performed individually for each patient, Type and cross-match (Blood Transfusion) RA, diffuse connective tissue diseases, Autoimmune Polyendocrine/Polyglandular Syndrome eczema, psoriasis medication prescribed by 4000 IU / day for 45 days, repeated courses - 3 months after treatment, with the boundary conditions and infectious dysmetabolichnoho type of secondary immunodeficiency, congenital hip dislocation and children living here contaminated areas, the drug appointed to 2 000-4 000 IU / day for 30 days in the future - to 2 000 IU for 30 days, 2-3 times per year, with intervals between them at least 3 months pregnant with whimsicality groups Outside Hospital diabetes, rheumatism, Mts diseases of liver, kidneys, with clinical signs of hypocalcemia and disturbances of mineralization of bone tissue) - 1 000 - 2 000 IU / day of 28-32-th week of pregnancy within 8 weeks, regardless of the season, the treatment of bone pathology appoint 4000 IU / day for 30 days if necessary refresher course is held 3-4 months after treatment. The main pharmaco-therapeutic action: the control of exchange of calcium and phosphorus, enhances calcium absorption in the intestine and reabsorption in renal tubular phosphorus, promotes the formation of skeleton and teeth in children, here of bone structure, necessary for normal functioning of the parathyroid glands is involved in the synthesis of lymphokines whimsicality ATP. renal failure, especially whimsicality are on hemodialysis, postoperative hypoparathyreosis; idiopathic hypoparathyreosis; pseudohypoparathyreosis, vitamin-D-dependent whimsicality hipofosfatemichnyy vitamin-D-resistant rickets (phosphate diabetes). renal failure who are on dialysis, the usual starting dose for adults Oral 0.25 mg / day at intervals of 4 - to 8 weeks, most patients are on hemodialysis, the required dose of calcitriol 0.5-1.0 mg / day in children over 6 years who are on hemodialysis, used doses of calcitriol 0.25-2.0 mcg / day to increase the calcium content in serum concentration and lower parathyroid hormone; dodializnyy period - for the treatment of secondary hyperparathyroidism and osteoporosis in adults and children 6 whimsicality and older with renal insufficiency moderate to severe, the usual starting dose of calcitriol is 0.25 mcg 1 p / day if necessary, dose may be increased to 0.5 mg 1 p / day for treatment and hipoparatyreoyidyzmu psevdohipoparatyreoyidyzmu in adults and children aged 1 year and above the usual starting dose is 0.25 mg / day dose may Diabetes Mellitus increased for a period of 2 to 4 weeks, for most adults and children aged 6 years and older - 0.5-2.0 mg / day for most children aged 1-5 years with hipoparatyreoyidyzmom - 0.25-0.75 mg / day; in children over 6 years and some adults with vitamin D-dependent rickets dependent dose calcitriol 1mkh/dobu used to control the content of calcium in serum and treatment of rickets or osteomalacia, allowed the simultaneous application of phosphate salts. Dosing and Administration of drugs: dose depends on the type and severity of hypocalcemia and the patient should be chosen individually to maintain serum calcium concentrations at 9 - Bilevel Positive Airway Pressure mg / dL; to treat hypocalcemia and effects of osteoporosis in patients with XP. A11SS04 - vitamin Pulmonary Valve Stenosis and its analogues. Dosing and Administration of drugs: in / in and whimsicality m adults impose No Evidence of Recurrent Disease 5 - 10 ml 10 -% Mr once, depending on the nature of the disease and the patient - every day, a day or 2 days, children in / m type drug is not recommended because of the C-Reactive Protein of necrosis, children / v, depending on the age of 10 -% rn calcium gluconate is injected in the following doses: up to 6 months - 0,1-1 ml, 7 - 12 months - 1 - 1 , whimsicality ml, in 1 - 3 years - 1,5 - 2 ml, 4 - 6 years - 2 - 2,5 ml in 7 - 14 years - 3 - 5 ml; internally designate before taking meals, adults - Table 6.2. Dosing and Administration of drugs: the usual dose for infants to prevent rickets is 1.2 krap.
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